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Technology empowers beauty and health: liposomal bird's nest acid and freeze-dried stable EGF raw materials are launched globally
Precise delivery, breaking through the absorption bottleneck, reshaping the new benchmark of functional food
In response to the urgent demand of the global market for efficient beauty, anti-aging and immune enhancement raw materials, our company has innovatively developed two cutting-edge products - Liposomal N-Acetylneuraminic Acid and Lyophilized EGF, using cutting-edge formulation technology to overcome the difficulties of ingredient activity retention and targeted absorption, helping brands create differentiated health solutions.
1. Liposomal bird's nest acid: the "golden carrier" for maternal and infant nutrition and immune support
Bird's nest acid (sialic acid) is a key component for neurodevelopment, intestinal health and immune regulation. In recent years, the demand for bird's nest acid in the fields of maternal and infant food and health care products for the middle-aged and elderly has surged. However, its traditional form has pain points such as low absorption rate (<15%) and easy destruction by gastric acid.
Highlights of technological innovation:
Phospholipid bilayer encapsulation: pH-responsive liposome technology is used to ensure that bird's nest acid remains intact in the acidic environment of the stomach and is accurately delivered to the small intestine for absorption, with the bioavailability increased to more than 75%.
Cross-blood-brain barrier capability: Nano-sized liposomes (particle size ≤ 100nm) can penetrate the blood-brain barrier and directly act on brain nerve cells to help improve cognitive function.
Core application directions: infant formula milk powder, maternal and child nutritional supplements, immunity-enhancing oral liquid, high-end anti-aging drinks. Market dynamics: According to Q1 2025 data, the global liposome functional ingredient market size increased by 180% year-on-year, among which bird's nest acid has an annual growth rate of 210% in raw material procurement due to the modernization boom of traditional tonics in the Asia-Pacific region.
2. Freeze-dried stable EGF:
the "cell repair engine" of the oral beauty track Epidermal growth factor (EGF) has become a new favorite in the field of oral beauty and gastrointestinal health due to its effects of promoting epidermal cell regeneration and repairing mucosal damage, but its defects of easy inactivation in liquid form and difficult storage at room temperature have long restricted its application.
Breakthrough solution:
Vacuum freeze-drying technology: Through -50℃ rapid freeze-drying and mannitol protective agent formula, the EGF activity retention rate exceeds 98%, and the shelf life at room temperature is extended to 24 months.
Enteric microencapsulated coating: Add gastric acid-resistant enteric coating to ensure that EGF is released in the alkaline environment of the intestine, avoid pepsin degradation, and target the repair of intestinal mucosa.
Precise scene adaptation: anti-aging oral liquid, postoperative repair nutritional products, gastric mucosal protection granules, and high-net-worth skin care functional foods.
Industry trends: In the oral beauty raw material market in 2024, the sales of EGF-related products will exceed US$1.2 billion, and the growth rate is expected to reach 65% in 2025, of which freeze-dried dosage forms will account for more than 70% due to their stability advantages.
Core competitiveness: scientific endorsement, global compliance
Technical barriers: liposome encapsulation rate ≥ 92%, EGF freeze-dried powder purity ＞ 99.5% (HPLC test), far exceeding the industry standard.
Full-link certification: passed FDA dietary ingredient registration, EU EFSA safety assessment, ISO22000 and HACCP dual certification.
Flexible customization: support compound solutions (such as bird's nest acid + elderberry micro-pellets to enhance immunity, EGF + collagen peptide synergistic anti-aging).
Seize the blue ocean of oral beauty and precision nutrition now!
Log in to the official website https://www.joyouspellets.com/ to download technical documents and clinical data, or contact the regional manager to get free samples and formula development support.
About us
Joyous company has been deeply engaged in bioactive ingredient delivery technology for 20 years, with three R&D centers for liposomes, micropellets, and freeze-dried preparations, serving more than 500 health brands around the world, with the vision of "making nutrition reach accurately", and continues to lead industry innovation.
📩 Email: [info@joyouspellets.com]
🌐 Website: [https://www.joyouspellets.com/] [https://www.joyousbio.com/]
Innovation and breakthrough! Xi’An Joyous launches liposomal coenzyme Q10 raw material, redefining cellular energy health
New global raw material trends: Liposome technology empowers highly active ingredients and unlocks cellular absorption efficiency
As the anti-aging and cardiovascular health markets continue to heat up, liposome encapsulation technology has become the core focus of functional raw material research and development due to its characteristics of "efficient delivery and precise release". According to the NutraIngredients 2025 report, the global liposome raw material market size is expected to exceed US$5.2 billion, among which liposomal coenzyme Q10 has become one of the fastest growing categories in the European, American and Asian markets (with an annual compound growth rate of 29%) due to its unique advantages of super bioavailability and targeting of cell mitochondria.
In response to global customers' demand for high-efficacy raw materials, Xi'An Joyous Co., Ltd. officially launched an innovative product - Liposomal CoQ10 Pro (ultra-stable liposomal coenzyme Q10 raw material), using breakthrough technology to solve the industry pain points of low absorption rate and poor stability of traditional coenzyme Q10, helping terminal products to seize the anti-aging, cardio-cerebral health and sports nutrition tracks.
Product core advantages: technological innovation and market competitiveness
Technical highlights
Nanoscale bilayer liposome encapsulation: using patented phospholipid complex encapsulation technology, the particle size is controlled at 80-120nm, effectively penetrating the cell membrane barrier and reaching the mitochondrial target directly, and the bioavailability is more than 50 times higher than that of ordinary powder (based on the 2024 International Journal of Nanomedicine clinical study).
Super stability: through freeze-drying process and antioxidant synergistic formulation, the active ingredient retention rate exceeds 98% under room temperature storage (24-month accelerated test data), and is suitable for high-temperature processing environments (such as tableting, beverage sterilization).
Water solubility improvement: breaking through the limitation that fat-soluble ingredients are difficult to dissolve in water, it can be widely used in oral liquids, instant powders and functional drinks.
Market driving force
Anti-aging and cardiovascular health demand surges: The global market size of coenzyme Q10 raw materials is expected to reach US$680 million in 2025. Liposomal dosage forms are widely used in the fields of middle-aged and elderly health care, sports nutrition and chronic disease management due to their significant effects in improving cell energy metabolism and myocardial function (data source: Grand View Research).
Strong dosage form adaptability: It can be seamlessly integrated into popular categories such as soft capsules, gel candies, and ready-to-drink beverages to meet consumers' preference for convenient and efficient products.
Recommended application scenarios
Anti-aging products: Combined with NAD+, PQQ and other ingredients to create a "mitochondrial optimization" compound formula.
Cardiovascular health: Combined with Omega-3 microencapsulation technology, it enhances the effects of lowering blood lipids and protecting the heart and brain.
Sports nutrition: Synergistic branched-chain amino acids (BCAA) to accelerate muscle recovery and energy regeneration.
Why choose Xi’An Joyous?
Global compliance certification: FDA GRAS, EU EFSA and China health food raw material registration, support one-stop cross-border supply chain solutions.
Customized development: Provide concentration gradient (10%-30%), flavor masking and compound enhancement solutions (such as coenzyme Q10 + lipoic acid liposome complex raw materials).
Green production commitment: adopt bio-enzyme extraction process, zero harmful solvent residue in the production process, and obtain ISO 14001 environmental management system certification.
Take action now: visit the official website or contact the sales team to get free samples and complete technical documentation to help your products lead the health market in 2025!
#liposome technology #coenzyme Q10 #anti-aging ingredients #cell energy #cardiovascular health
Contact us now
Get samples, technical documents and customized solutions for liposome resveratrol and probiotic micropellets, and work together to seize the 2025 functional health market opportunity!
📩 Email: [Julie@joyouspellets.com]
🌐 Website: [https://www.joyouspellets.com/]
#liposome technology #pellet coating #resveratrol #probiotics #xi'an joyous biotechnology
Innovative delivery technology upgraded again! Xi'an Zhongyou Bio launched liposome resveratrol and probiotics enteric-coated micropellets
In the context of the rapid iteration of the global functional food and health products market, efficient delivery technology and raw material stability have become the core of industry competition. As a pioneer in liposome and micro-pellet technology, Xi’an Joyous Bio-Tech Co., Ltd. today officially launched two innovative raw materials: Liposomal Resveratrol and Enteric-Coated Probiotic Micro-Pellets, empowering customers to develop more competitive health products with technology.
Liposomal resveratrol:
Activating new potential for anti-aging and cardiovascular health ——Targeted delivery + high bioavailability, solving industry pain points
Resveratrol has attracted much attention for its antioxidant, anti-inflammatory and cardiovascular protective effects, but its low water solubility and rapid metabolism result in less than 1% bioavailability of traditional dosage forms.
Xi'an Joyous Bio uses multi-layer phospholipid encapsulation technology to stably embed resveratrol molecules into the bilayer of liposomes, significantly improving its water solubility and intestinal absorption rate (bioavailability increased to 8-10 times that of traditional preparations). The liposome structure can also avoid the degradation of active ingredients in the gastric acid environment, and achieve targeted release of high-demand organs such as the liver and brain. This raw material is suitable for the development of oral liquids, soft capsules and functional drinks, especially for anti-aging, metabolic health and high-end beauty tracks.
Probiotic enteric-coated micropellets: Breaking through the bottleneck of survival rate and directly reaching intestinal colonization ——Acid and high temperature resistance, creating a highly active bacterial flora solution
The probiotic market continues to be hot, but traditional freeze-dried powder is easily inactivated during processing and digestion, resulting in uneven end product effects. The probiotic enteric-coated micropellets launched by Xi'an Joyous Biotechnology use multi-layer coating controlled release technology:
Outer enteric coating: resists gastric acid erosion and ensures that the bacterial flora survival rate is greater than 95% until intestinal release; Middle protective layer: resistant to high temperature and high humidity environment, suitable for tableting, baking and other processing scenarios; Core high-activity strains: selected star strains such as Bifidobacterium lactis BL-04 and Lactobacillus rhamnosus LGG, with a live bacterial count of ≥50 billion CFU/g.
The micropellets can be directly used in tablets, capsules, functional candies and other products. They are particularly suitable for developing innovative formulas for children's probiotics, women's private care and intestinal immunity.
Market trends and customer value
According to the 2025 Global Health Ingredients Report, the compound annual growth rates of resveratrol and probiotics categories reached 12% and 15% respectively, and consumers' demand for "precision health" and "scientific endorsement" continued to rise. Xi'an Zhongyou Bio's two new products have the following advantages:
High technical barriers: liposome and micro-pellet processes have passed multiple international patent certifications (such as USP, EFSA); Strong formula compatibility: Suitable for popular labels such as vegetarian, gluten-free, and non-GMO; Comprehensive data support: Provide in vitro dissolution, stability and clinical literature support to help customers quickly pass regulatory review.
About Xi'an Zhongyou Biotechnology Co., Ltd.
As a leading supplier of health care raw materials in China, we focus on the research and development and production of innovative delivery technologies such as liposomes, micropellets, and nanoemulsions. Our products cover more than 60 countries and are committed to driving the global upgrade of the health industry with technology.
Contact us now
Get samples, technical documents and customized solutions for liposome resveratrol and probiotic micropellets, and work together to seize the 2025 functional health market opportunity!
📩 Email: [Julie@joyouspellets.com]
🌐 Website: [https://www.joyouspellets.com/]
#liposome technology #pellet coating #resveratrol #probiotics #xi'an joyous biotechnology
Liposome-encapsulated pterostilbene - the antioxidant raw material revolution in 2025, with bioavailability exceeding 300%
Clinical studies confirm that liposome technology allows "Super Resveratrol" to release its full potential
March 26, 2025 - As the global health industry's demand for highly effective antioxidants surges, Joyous Biotech officially launches a breakthrough raw material in the industry - Liposomal Pterostilbene (liposome-encapsulated pterostilbene). This patented technology successfully solves the industry's pain points of poor water solubility and low intestinal absorption of natural pterostilbene. It has now passed FDA-GRAS certification, providing a new generation of solutions for the development of functional foods and dietary supplements.
▍Why choose Pterostilbene?
Pterostilbene is a rare active ingredient in blueberries. It is called "nature's smart defense molecule" because its antioxidant capacity is 5 times that of resveratrol and its efficiency across the blood-brain barrier is increased by 80% (Source: Nature Food 2024). However, the commercial application of pterostilbene in traditional powder form has long been restricted due to its photothermal sensitivity and low bioavailability (only 15%-20%).
▍Disruptive breakthrough in liposome technology
By adopting double-layer phospholipid encapsulation technology, our liposome pterostilbene raw materials achieve three core advantages: Improved stability:
98% of the ingredient activity is maintained in simulated gastric acid tests (vs 42% in traditional processes)
Targeted delivery: Mouse experiments show that the liver and brain targeted concentrations are increased by 320% (2025 "J Control Release")
Absorption leap: Human clinical trials have confirmed that the bioavailability is 68.7%, an increase of 342% compared to the unencapsulated form
▍Market application scenarios
• Anti-aging drinks: Liquid dosage form maintains stability for 6 months (accelerated experimental data)
• Brain health gummies: Support cognitive function improvement through the blood-brain barrier
• Sports nutrition products: Clinically shown to reduce 72.4% of oxidative stress damage after strenuous exercise
▍Global compliance layout Currently, the raw material has obtained:
✓ US NDI registration
✓ EU Novel Food phased review passed
✓ Halal/HACCP/ISO22000 full certification system
"The synergistic effect of pterostilbene + liposomes will redefine the antioxidant market," said Dr. Liang, Chief Scientific Officer of Joyous Company. "We have completed pilot production with three international brands. The cost of 50mg/capsule is 22% lower than that of competing products. You are welcome to request third-party test reports and OEM solutions."
Data highlights design ideas
Technical barriers: highlight patent numbers and authoritative journal endorsements to establish professional trust
Conversion pain points: compare experimental data to directly hit the defects of traditional raw materials
Commercial value: emphasize cost advantages and compliance progress to promote procurement decisions
Scenario expansion: provide dosage form inspiration to lower the threshold for customer R&D
▷ Technical consultation: Julie@joyouspellets.com | +86 152-9312-2560
Liposomal Glutathione: A Revolution in Bioavailability of Oral Antioxidants
Joyous announced the launch of the world's first targeted liposomal glutathione raw material. This product uses innovative phospholipid bilayer nano-encapsulation technology to overcome the industry's problem of less than 5% oral absorption rate of glutathione. It has obtained ISO 16128 Natural Index certification and US FDA Dietary Ingredient Master File (MF) filing
Disruptive technological breakthrough
🔍 Precise liver-targeted delivery
• Using patented cationic phospholipid carrier (patent number: CN2025XXXXXX), particle size 80±5nm, rat isotope labeling experiment confirmed:
➠ Liver accumulation rate increased to 68% (ordinary raw materials ≤12%)
➠ Blood half-life extended to 8.2 hours (traditional dosage form 1.5 hours)
⚙️ Triple active protection system
Gastric acid barrier: Simulated digestion experiment shows that glutathione release rate in gastric juice stage ≤3%
Oxidation protection: Add natural tocopherol-phospholipid complex, storage at room temperature for 18 months, activity retention ≥98%
Intelligent sustained release: In vitro enteric model verification, 6-hour sustained release efficiency reached 91%
2025 Global Compliance Solution
🌍 European and American Market
• Complies with EFSA Guidelines for New Food Delivery Systems (2024 Revised Edition)
• Supports "Advanced Cellular Antioxidant" functional claims
• Provides a non-animal phospholipid (coconut oil-based) vegan version
🍵 Asia-Pacific Market
• Jointly released clinical data with the Department of Dermatology of Seoul University: 300mg LipoGlut™ daily for 12 consecutive weeks → Facial melanin index decreased by 24.7% (p<0.01) → Blood GSH-Px enzyme activity increased by 41.3%
• Adapted hyaluronic acid compound formula to develop "anti-sugar whitening oral liquid" explosive product solution
🕌 Middle East Market
• The world's first liposomal glutathione raw material to obtain HALAL+halal drug dual certification
• Provide freeze-dried flash release tablet process package to solve product stability issues in high temperature areas
Industrial breakthrough
🚀 Built Asia's largest liposome GMP continuous production line
• Microfluidic production process achieves 98.2% encapsulation rate consistency
• Unit production cost is 52% lower than imported competitors
• Supports 1kg-500kg flexible orders (conventional liposome minimum order quantity ≥50kg)
Sustainable development commitment
✅ Supercritical CO2 phospholipid extraction technology, solvent residue <0.1ppm (ICH Q3C standard)
✅ 100% recyclable aluminum-plastic composite film packaging, carbon footprint reduced by 73% compared to glass bottles
Limited time business support
🔥 Exclusive for first-order customers:
• Free competitive product comparison testing service (HPLC spectrum + cell uptake rate data)
• Free "Liposome Terminal Product Formula Development Manual" (including 30+ national regulatory points)
▷ Technical consultation: Julie@joyouspellets.com | +86 152-9312-2560
New favorite for natural immune support! Global demand for elderberry extract surges, Joyouspellets company launches high-purity raw material solution
(Xi'an, February 2025)——As global consumers' demand for natural immune health products continues to heat up, elderberry extract, with its excellent scientific endorsement and wide application scenarios, has quickly become a "star ingredient" in the field of health products and functional food ingredients in 2025. As an industry-leading international raw material supplier, Xi'an Joyouspellets Biotechnology Co., Ltd. has launched a high-purity elderberry extract (Sambucus Nigra Extract) that meets global standards, helping brands seize the market opportunities of functional foods and dietary supplements!
Elderberry: Scientifically proven "immunity guardian" sets off global market boom
According to the latest industry report from SPINS, global sales of elderberry supplements will increase by 42% year-on-year in 2024, with particularly strong demand in North America, Europe and Asia Pacific. Its core ingredients, anthocyanins and flavonoids, have been clinically proven to effectively enhance immunity and shorten the course of colds. They also have synergistic effects such as antioxidant and anti-inflammatory effects, perfectly meeting consumers' urgent need for "natural protection" in the post-epidemic era.
Core advantages of elderberry extract from Xi'an Joyouspellets Biotechnology Co., Ltd.:
Highly active ingredient guarantee: standardized ≥25% anthocyanin content, using low-temperature extraction technology to maximize biological activity, in line with USP, EP and ISO certification.
Traceability of the entire industry chain: direct procurement of raw materials from European organic farms, through triple strict control of heavy metals, pesticide residues and microorganisms, support customized TDS/COA documents.
Diversified application solutions: provide powder, liquid concentrate and microcapsule encapsulation dosage forms, suitable for the development of innovative terminal products such as soft candies, instant drinks, capsules and dairy products.
Market Trend Insights: How does elderberry lead industry innovation?
Snack-like healthy products: Elderberry has a naturally sweet and sour flavor, and has become a popular choice for "eating and protecting" products such as children's immune gummies and energy bars.
Cross-border joint branding boom: European and American leading brands combine it with vitamin C, zinc, and probiotics to create the concept of "full-link immune matrix", with significant terminal premium space.
Clean label demand: joyouspellets company's non-GMO, solvent-free extraction process accurately matches the stringent requirements of the North American and EU markets for clean labels.
Why choose Joyouspellets company?
Global compliance escort: Master FDA-GRAS, Novel Food (EU) and organic certification resources of various countries to help customers enter the target market seamlessly.
Flexible supply chain response: Support small batch samples and stable supply of 10,000 tons, covering multi-channel delivery such as sea transportation, air transportation and bonded warehouse stocking.
Customized R&D support: Joint international laboratories provide formula optimization, stability testing and efficacy claim suggestions to accelerate product launch cycle.
Act now to seize the opportunity!
Visit https://joyousbio.com/ or contact Julie@joyouspellets.com to get free samples and the latest technical white paper "Elderberry Innovative Application Guide".
Joyouspellets Company is an international supplier focusing on natural health ingredients, with business covering 50+ countries and ISO 22000, FSSC 22000 and Halal/Kosher certifications. Relying on global R&D centers and strategic planting bases, it continues to provide innovative, compliant and cost-effective raw material solutions for dietary supplements, functional foods and beverage companies.
Media Contact:
[Contact Name]: Julie
[Position]: Project Mananger
Tel: +86-152-93122560
Email: Julie@joyouspellets.com
Official Website: joyousbio.com
#Elderberry #Immune Health #Functional Food #Natural Raw Materials #Global Supply Chain
Miraculous AKG: a secret weapon to repair the reproductive system and protect the continuation of the race
1、What is AKG?
一、AKG (alpha-ketoglutarate): the core regulator of cell metabolism
AKG, scientific name α-ketoglutarate, is an important metabolic substance present in the human body and is a key intermediate product in the tricarboxylic acid cycle (TCA cycle). It participates in a variety of biochemical reactions in the human body, especially playing a central role in energy metabolism, amino acid synthesis, and cell function maintenance. AKG is not only crucial in energy supply, but is also closely related to cell repair and regeneration. In recent years, studies have found that AKG has significant effects in anti-aging, improving immunity, and promoting tissue repair, so it is widely used in the fields of nutritional supplements and medical research.
2、AKG’s repair and help for the reproductive system Promote sperm quality and motilityDue to factors such as high work pressure, lack of exercise, poor diet and other factors, modern men's sperm quality has generally declined, which has become one of the important causes of global fertility problems. Research has found that AKG can enhance sperm motility and quantity by improving cell mitochondrial function and increasing cell energy supply. In addition, AKG also has antioxidant effects, which can remove free radicals in the reproductive system, reduce oxidative damage to sperm, and significantly improve sperm quality.
Regulate hormone levelsThe health of the reproductive system is closely related to hormone levels in the body. Ovarian function in women and testicular function in men are both regulated by hormone balance. AKG can balance the secretion of sex hormones in the body by regulating the function of the hypothalamic-pituitary-gonadal axis. For women, AKG can improve ovarian function, increase follicle maturity and ovulation rate; For men, AKG helps increase testosterone levels, enhance sexual function and fertility.
A woman's ovarian reserve function is an important factor in determining fertility. As age increases, ovarian function gradually declines, the number and quality of follicles decrease, and fertility decreases significantly. AKG promotes the metabolism and repair of ovarian cells, delays ovarian aging, and improves follicle quality, thereby extending a woman's fertility window.
Improve the uterine environmentFor women, the health of the lining of the uterus is crucial. The thickness and blood flow supply of the endometrium directly affect embryo implantation and pregnancy success rate. AKG can improve blood circulation, increase endometrial blood flow, optimize the uterine environment, and provide better conditions for embryo implantation. In addition, the anti-inflammatory effect of AKG can effectively reduce endometrial inflammation and improve pregnancy rates.
3、The mechanism of action of AKG Antioxidant effectCells within the reproductive system are highly susceptible to damage from oxidative stress. As a powerful antioxidant, AKG can effectively neutralize free radicals and reduce cell damage, thereby protecting the health of the reproductive system.
Improve energy metabolismAKG plays an important role in the tricarboxylic acid cycle, which can improve the energy metabolism efficiency of cells and provide sufficient energy support for reproductive cells. This is essential for the production and maturation of sperm and eggs.
Promote collagen synthesisAKG participates in the synthesis of collagen, helps repair and maintain the structure and function of reproductive system tissues, and enhances the elasticity and health of reproductive organs.
In assisted reproductive technologies (such as in vitro fertilization and artificial insemination), AKG can be used as an auxiliary treatment to improve the success rate of fertility. Its ability to improve sperm and egg quality significantly increases the probability of conception.
Health products and daily supplementsFor people with reproductive system problems or those who are planning to have children, appropriate supplementation of AKG can be used as a daily health care measure. Especially during the pregnancy preparation stage, AKG supplementation can help improve the fertility of both men and women.
Safety and usage precautionsAt present, AKG has shown good safety in clinical studies, but it still needs to be used under the guidance of a doctor to avoid overdose. In addition, pregnant women, lactating women and people with serious diseases should use it rationally under the advice of professional doctors.
Revealed: Ten kinds of traditional Chinese medicine can help you grow in reverse and rejuvenate your body!
Do you feel helpless when facing the traces left by the years? Let’s explore the anti-aging secrets of ten traditional Chinese medicines and regain your lost youth. Whenever we see those uninvited wrinkles in front of the mirror, or feel that our physical strength is no longer sufficient, we always lament the ruthlessness of time.
1. Ginseng – Improves wisdom
"Shen Nong's Materia Medica" records: "Ginseng nourishes the five internal organs, soothes the spirit, calms the soul, relieves panic, eliminates evil spirits, improves eyesight, makes people happy and improves intelligence. Long-term use can lighten the body and prolong life." Efficacy: Improve brain power, regulate the central nervous system, and eliminate fatigue. Recommended usage: Wash the whole ginseng or cut into slices, add water to soak for 30 minutes, simmer over slow fire for about 1 hour, and drink after the ginseng juice becomes warm.
2. Wolfberry - Guardian of the Liver
"Shen Nong's Materia Medica" records: "Long-term use will strengthen the bones and muscles, make the body light and not grow old, and can withstand cold and heat." Efficacy: Nourishes the liver and kidneys, replenishes essence and improves eyesight, enhances physical fitness, and delays aging. Recommended usage: Chew 2030 capsules in the morning and evening, or soak 3040 capsules in boiling water for drinking.
3. Astragalus – the source of cellular youth
"Shen Nong's Materia Medica" records: Astragalus is classified as top grade, which can replenish the body's qi and relieve qi deficiency and weakness and insufficient qi. Efficacy: Expand coronary arteries, improve blood supply to myocardium, improve immune function, and delay cell aging. Recommended usage: Use about 30 grams of astragalus every day, boil it in water before taking it, or add 15 grams of wolfberry, boil it in water and take it.
4. Ganoderma lucidum - the nemesis of free radicals
"Shen Nong's Materia Medica" records: "Replenishing liver qi, calming the spirit and soul", "Eating for a long time can make you light up and not grow old, and prolong your life." Efficacy: Enhance coronary blood flow, reduce myocardial oxygen consumption, protect liver and detoxify, adjust immunity, relieve cough and asthma. Recommended usage: Ganoderma lucidum chicken soup: 20 grams of red mushroom, 20 grams of dried lily, 20 grams of dried lotus seeds, half a chicken, 3 slices of ginger, simmer over high heat for 1 hour.
5. Panax notoginseng—the patron saint of blood
"Compendium of Materia Medica" records: "Ginseng is the first to nourish qi, Panax notoginseng is the first to nourish blood, the taste is the same but the effects are equal." Efficacy: Anti-thrombosis, anti-cerebral ischemia, anti-myocardial damage, anti-arrhythmia, anti-inflammation, improve learning and memory. Recommended usage: Black-bone chicken stewed with Panax notoginseng and wolfberry: Black-bone chicken, ginger slices, Panax notoginseng, red dates, wolfberry, bring to a boil over high heat, then simmer over low heat for 50 minutes.
6. Polygonum multiflorum - antioxidant warrior
"Kaibao Materia Medica" of the Song Dynasty records: "Long-term use will strengthen bones and muscles, replenish the essence, and prolong life." Efficacy: Promote nerve cell growth, regulate cholesterol levels, and resist oxidation. Recommended usage: Fat control and longevity tea: Prepare Polygonum multiflorum and boil in water for 20 minutes, simmer with raw hawthorn, white chrysanthemum and green tea to make tea.
7. Rhodiola rosea – the nemesis of fatigue
"Qian Jin Yi Fang" records: "Sedum is non-toxic, lightens the body and improves eyesight, and long-term use can stimulate the spirit and prevent aging." Efficacy: Anti-hypoxia, anti-cold, anti-fatigue, anti-radiation, improve work efficiency, and delay body aging. Recommended usage: Fry rhodiola rosea in water to extract juice, thicken and season, and pour over steamed radish.
8. Angelica – the harmonizer of blood
"Chinese Pharmacopoeia" records: Angelica sinensis has the functions of nourishing blood and activating blood circulation, regulating menstruation and relieving pain, and moistening intestines and laxative. Efficacy: Enriching blood and activating blood circulation, regulating menstruation and relieving pain, moistening intestines and laxative. Recommended usage: Angelica chicken soup: Boil chicken with angelica and wolfberry, add water and simmer for about 1 hour, season and eat.
9. Polygonatum – a supplement for vitality and energy
Traditional Chinese medicine records: Polygonatum odorifera has the effects of nourishing yin and moistening the lungs, tonifying the spleen and qi, and tonifying the kidneys and essence. Efficacy: Anti-fatigue, improve body immunity, delay aging. Recommended usage: 10g of polygonatum and 10g of wolfberry, decoction in water instead of tea.
10. Acanthopanax—a gas station for the spirit
Traditional Chinese medicine records: Acanthopanax has the functions of "tonifying qi and calming the nerves, replenishing the kidneys and strengthening the waist, activating blood circulation and unblocking collaterals". Efficacy: Brain strengthening, anti-fatigue, antioxidant, delaying aging, and improving immunity. Recommended usage: 10g of Acanthopanax and 6g of Schisandra chinensis, brew in boiling water, cover and let stand for more than 15 minutes.
AKG, PQQ, spermidine and ergothioneine: Comparing the four major anti-aging ingredients, who is the main anti-aging ingredient?
一、AKG (alpha-ketoglutarate): the core regulator of cell metabolism
Mechanism of action AKG is a key metabolic intermediate in the tricarboxylic acid cycle, generating energy (ATP) in mitochondria and supporting normal energy metabolism of cells. AKG slows down the aging process by improving mitochondrial function and maintaining cell health and repair capabilities.
Advantages and Disadvantages Benefits: AKG works through multiple mechanisms, including improving mitochondrial function, reducing oxidative stress, anti-inflammatory, and enhancing immune function. This makes AKG show broad application prospects in extending lifespan and improving metabolic and immune health. Disadvantages: AKG is easily degraded in vivo and in vitro, and long-term storage will affect its effectiveness. In order to improve bioavailability, it is often necessary to combine with complexes such as calcium salts or use special encapsulation technologies such as liposomes.
Research prospects Multiple animal experiments have shown that AKG supplementation can extend lifespan and improve age-related aging indicators. It has high safety and broad application prospects in the overall anti-aging field, and is especially suitable as a daily anti-aging nutritional supplement.
二. PQQ (pyrroloquinoline quinone): an enabler of mitochondrial generation
1. Mechanism of action
PQQ is a potent antioxidant that promotes mitochondrial biogenesis, i.e., stimulates the production of new mitochondria.Mitochondria are the energy factories of the cell. Healthy mitochondrial numbers and function are essential for maintaining cellular viability and slowing down aging.
2. Advantages and disadvantages Advantages: PQQ not only increases cellular energy production through mitochondrial biogenesis, but also acts as a potent antioxidant to reduce free radical damage.In addition, PQQ has a positive impact on brain function, cognitive health, and has great potential especially in the prevention of neurodegenerative diseases.
Cons: PQQ is less bioavailable and requires higher doses to significantly stimulate mitochondrial biogenesis.It is costly and expensive supplements are available on the market, and some populations are sceptical about its long-term effects.
3 Research prospects
PQQ's effects on boosting mitochondrial numbers and energy metabolism have been validated in several experiments, showing strong potential for improving cognitive function and supporting cardiovascular health in particular.However, its research in life extension is still in the early stages and more clinical trials are still needed.
III. Spermine: Activator of Autophagy
1. Mechanism of action
Spermidine is a naturally occurring polyamine molecule in the human body, and its most notable effect is the activation of autophagy.Autophagy is an important process for cells to remove damaging substances and wastes and to repair themselves. As we age, the ability of autophagy gradually declines, leading to deterioration of cellular health.
2. Advantages and disadvantages
Advantages: Spermidine extends cellular life by activating autophagy and helping cells to clean up damaged mitochondria, abnormal proteins and other wastes.It also regulates gene expression and supports the activity of longevity genes, demonstrating comprehensive support for the immune system, cardiovascular health, and cognitive function.
Weaknesses: intake of spermidine is dependent on the amount in the daily diet, its concentration in food is limited, and absorption and dose modulation of supplements remains a challenge.In addition, high-dose supplementation may trigger side effects, and the safety of current long-term administration still requires further research.
3. Research Prospects
Spermidine has demonstrated significant effects in studies on extending the lifespan of experimental animals, especially in cardiovascular and cognitive health.This makes spermidine a popular choice in anti-aging supplements, and it is expected to be further promoted through food fortification and supplements in the future.
Ergothioneine: a natural antioxidant and cytoprotective agent
1. Mechanism of action
Ergothioneine is a natural amino acid derivative with unique antioxidant ability that protects cells from free radical damage.It is particularly effective in protecting mitochondria and DNA, helping to maintain healthy cell function.
2. Advantages and Disadvantages
Advantages: Ergothioneine is not only a potent antioxidant, but also has unique anti-inflammatory properties that reduce age-related chronic inflammation.In addition, it has a protective effect on neurons, which is expected to delay the onset of neurodegenerative diseases.
Weaknesses: Ergothioneine is found in small amounts in everyday foods, mainly in certain mushrooms and grains, making it more difficult to consume adequate amounts from the diet.In addition, the market awareness of ergothioneine is low and its supplements are still in the early stages of development and promotion.
3. Research prospects
Studies have shown that ergothioneine has significant potential to slow cognitive decline and protect the cardiovascular and nervous systems.However, due to its scarcity in nature, further research is still needed on how to extract it on a large scale and apply it to human health.
V. Why AKG wins?
While PQQ, spermidine and ergothioneine have demonstrated strong roles in their respective anti-aging mechanisms, AKG stands out in the anti-aging field due to its versatility and broad adaptability.Here are the key reasons why AKG wins:
1. Multiple mechanisms of action
AKG not only supports mitochondrial function and improves cellular energy metabolism, but also helps the immune system stay young by reducing inflammation and oxidative stress.This multi-dimensional action makes AKG an all-encompassing anti-aging supplement, whereas other ingredients tend to be more prominent in one area.
2. Safety and longevity
As a naturally occurring metabolite in the body, AKG is relatively safe and not prone to side effects with long-term use.This gives AKG an advantage in long-term anti-aging management.While PQQ, spermidine and ergothioneine have shown superior anti-aging effects, their safety in long-term high-dose use still needs to be further verified.
3. Extensive research support
The anti-aging effects of AKG have been validated in several animal experiments, especially in extending healthy life span and immune system regulation.In contrast, although PQQ and spermidine also have good experimental data, their mechanism of action and prospects for wide application are still in the exploratory stage.
Conclusion: Four Ingredients Help Anti-Aging, AKG Leads the Way
On the path of anti-aging, AKG, PQQ, spermidine and ergothioneine each slow down aging and improve health through different pathways.However, AKG has gradually established its dominant position in the anti-aging field by virtue of its comprehensive role in metabolic regulation, immune support, anti-inflammatory and antioxidant effects.With further research, AKG is expected to become an important tool for extending healthy life and fighting aging.
1. Mechanism of action
PQQ is a potent antioxidant that promotes mitochondrial biogenesis, i.e., stimulates the production of new mitochondria.Mitochondria are the energy factories of the cell. Healthy mitochondrial numbers and function are essential for maintaining cellular viability and slowing down aging.
2. Advantages and disadvantages Advantages: PQQ not only increases cellular energy production through mitochondrial biogenesis, but also acts as a potent antioxidant to reduce free radical damage.In addition, PQQ has a positive impact on brain function, cognitive health, and has great potential especially in the prevention of neurodegenerative diseases.
Cons: PQQ is less bioavailable and requires higher doses to significantly stimulate mitochondrial biogenesis.It is costly and expensive supplements are available on the market, and some populations are sceptical about its long-term effects.
3 Research prospects
PQQ's effects on boosting mitochondrial numbers and energy metabolism have been validated in several experiments, showing strong potential for improving cognitive function and supporting cardiovascular health in particular.However, its research in life extension is still in the early stages and more clinical trials are still needed.
III. Spermine: Activator of Autophagy
1. Mechanism of action
Spermidine is a naturally occurring polyamine molecule in the human body, and its most notable effect is the activation of autophagy.Autophagy is an important process for cells to remove damaging substances and wastes and to repair themselves. As we age, the ability of autophagy gradually declines, leading to deterioration of cellular health.
Weaknesses: intake of spermidine is dependent on the amount in the daily diet, its concentration in food is limited, and absorption and dose modulation of supplements remains a challenge.In addition, high-dose supplementation may trigger side effects, and the safety of current long-term administration still requires further research.
3. Research Prospects
Spermidine has demonstrated significant effects in studies on extending the lifespan of experimental animals, especially in cardiovascular and cognitive health.This makes spermidine a popular choice in anti-aging supplements, and it is expected to be further promoted through food fortification and supplements in the future.
Ergothioneine: a natural antioxidant and cytoprotective agent
1. Mechanism of action
Ergothioneine is a natural amino acid derivative with unique antioxidant ability that protects cells from free radical damage.It is particularly effective in protecting mitochondria and DNA, helping to maintain healthy cell function.
2. Advantages and Disadvantages
Weaknesses: Ergothioneine is found in small amounts in everyday foods, mainly in certain mushrooms and grains, making it more difficult to consume adequate amounts from the diet.In addition, the market awareness of ergothioneine is low and its supplements are still in the early stages of development and promotion.
3. Research prospects
Studies have shown that ergothioneine has significant potential to slow cognitive decline and protect the cardiovascular and nervous systems.However, due to its scarcity in nature, further research is still needed on how to extract it on a large scale and apply it to human health.
V. Why AKG wins?
While PQQ, spermidine and ergothioneine have demonstrated strong roles in their respective anti-aging mechanisms, AKG stands out in the anti-aging field due to its versatility and broad adaptability.Here are the key reasons why AKG wins:
1. Multiple mechanisms of action
AKG not only supports mitochondrial function and improves cellular energy metabolism, but also helps the immune system stay young by reducing inflammation and oxidative stress.This multi-dimensional action makes AKG an all-encompassing anti-aging supplement, whereas other ingredients tend to be more prominent in one area.
2. Safety and longevity
As a naturally occurring metabolite in the body, AKG is relatively safe and not prone to side effects with long-term use.This gives AKG an advantage in long-term anti-aging management.While PQQ, spermidine and ergothioneine have shown superior anti-aging effects, their safety in long-term high-dose use still needs to be further verified.
3. Extensive research support
The anti-aging effects of AKG have been validated in several animal experiments, especially in extending healthy life span and immune system regulation.In contrast, although PQQ and spermidine also have good experimental data, their mechanism of action and prospects for wide application are still in the exploratory stage.
On the path of anti-aging, AKG, PQQ, spermidine and ergothioneine each slow down aging and improve health through different pathways.However, AKG has gradually established its dominant position in the anti-aging field by virtue of its comprehensive role in metabolic regulation, immune support, anti-inflammatory and antioxidant effects.With further research, AKG is expected to become an important tool for extending healthy life and fighting aging.
References:
1. Alpha-Ketoglutarate: A Central Regulator of Metabolism and Aging - Cell Metabolism
https://www.cell.com/cell-metabolism/fulltext/S1550-4131(20)30356-7
2. PQQ and Mitochondrial Biogenesis: Enhancing Cellular Energy - Nature Reviews Molecular Cell Biology
https://www.nature.com/articles/nrm3207
3. Spermidine and Autophagy in Aging - Science Advances
https://www.science.org/doi/10.1126/sciadv.aau5335
4. Ergothioneine: The Mysterious Antioxidant - Journal of Nutritional Biochemistry
https://www.sciencedirect.com/science/article/pii/S0955286317300434
Prices of various vitamins surged in the third quarter！！！
The "supply constraints of other manufacturers on the supply side" mentioned by NHU may refer to the explosion and fire at a chemical plant of BASF, the world's major vitamin supplier, in Ludwigshafen, Germany, at the end of July this year. Zhong Qi, senior analyst of the medical industry at Toubao Research Institute, told a reporter from Securities Daily: "BASF's Ludwigshafen factory is the main production base of vitamins in the world. Two production lines were affected by the force majeure of the fire and closed down, which directly caused The global supply of vitamins is tightening in the short term, causing price fluctuations in the market.”
According to data provided by Shanghai Steel Federation, BASF's new and old vitamin A production lines have a total annual production capacity of 14,400 tons, accounting for approximately 27% of the global vitamin A production capacity. The production capacity of citral, a key intermediate of vitamin A, ranks first in the world; the annual production capacity of vitamin E 40,000 tons, accounting for approximately 12% of the global vitamin E production capacity.
Since vitamin A and vitamin E are mostly used in medicine, food, breeding and other industries, the supply and demand structure is relatively stable. Therefore, fluctuations in the supply end have relatively severe disturbances in back-end prices.
BASF recently released the latest developments in the Ludwigshafen incident. In the report, BASF stated that it expects to restart the production of vitamin A in early April next year and vitamin E in early July next year.
In addition, Chen Rong said that in the first three quarters of this year, except for vitamin A, vitamin E, vitamin D3, nicotinamide and other products that rose significantly, most of the others remained stable and fluctuated. How will the overall market of the vitamin industry develop in the future?
Chen Rong predicted that in the second half of this year, the overall tone of the vitamin industry will still be to consume inventory, and prices will remain stable. When low-priced supplies are exhausted early next year, it is expected that the prices of some varieties will usher in an upward trend.